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Seropositive rheumatoid arthritis

RHEUMA_SEROPOS

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

9984

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RHEUMA_SEROPOS

Control definitions

Control exclude RHEUMA_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze DF9

Similar endpoints

List of similar endpoints to Seropositive rheumatoid arthritis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 9984 6826 3158
Unadjusted prevalence (%) 2.42 2.96 1.74
Mean age at first event (years) 54.23 52.42 58.15

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: RHEUMA_SEROPOS – Seropositive rheumatoid arthritis
GWS hits:

Survival analyses between endpoints

Plot

before Seropositive rheumatoid arthritis
after Seropositive rheumatoid arthritis

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Drugs most likely to be purchased after Seropositive rheumatoid arthritis

Endpoint not on priority list, no data to show.