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Seropositive rheumatoid arthritis

RHEUMA_SEROPOS

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

9984

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RHEUMA_SEROPOS

Control definitions

Control exclude RHEUMA_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze DF9

Similar endpoints

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List of similar endpoints to Seropositive rheumatoid arthritis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 9984 6826 3158
Unadjusted prevalence (%) 2.42 2.96 1.74
Mean age at first event (years) 54.23 52.42 58.15

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

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Index endpoint: RHEUMA_SEROPOS – Seropositive rheumatoid arthritis
GWS hits:

Survival analyses between endpoints

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Plot

before Seropositive rheumatoid arthritis
after Seropositive rheumatoid arthritis

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Drugs most likely to be purchased after Seropositive rheumatoid arthritis

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Endpoint not on priority list, no data to show.