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Arthropathies

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_ARTHROPATHIES

joint disease: Any disorder of the joints.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M00-M25
Cause of death: ICD-10 M00-M25

2 out of 7 registries used, show all original rules.

143593

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Check minimum number of events None

143593

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Include endpoints

154198

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Remove individuals based on genotype QC

149334

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M13_ARTHROPATHIES

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 149334 87433 61901
Unadjusted prevalence (%) 36.25 37.97 34.06
Mean age at first event (years) 50.02 48.63 51.97

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.36 [1.25, 1.48] 1.7e-13 15784
15 years 0.01 1.02 [0.96, 1.09] 5.1e-1 6938
5 years 0.00 1.58 [1.48, 1.68] 5.5e-44 3034
1 year 0.00 2.61 [2.36, 2.89] 6.8e-75 937

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_ARTHROPATHIES – Arthropathies
GWS hits: 33

Survival analyses between endpoints

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Plot

before Arthropathies
after Arthropathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Arthropathies

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Endpoint not on priority list, no data to show.