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Polyarthropathies

DOID EFO MESH Endpoint Browser PheWeb

M13_POLYARTHROPATHIES

obsolete_juvenile idiopathic arthritis: ['A group of chronic, inflammatory childhood disorders of unknown etiology that primarily involve joints.']

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M05-M14
Cause of death: ICD-10 M05-M14

2 out of 7 registries used, show all original rules.

33185

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Check minimum number of events None

33185

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Include endpoints

36507

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Remove individuals based on genotype QC

35407

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M13_POLYARTHROPATHIES

Control definitions

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 35407 18929 16478
Unadjusted prevalence (%) 8.59 8.22 9.07
Mean age at first event (years) 53.13 49.43 57.38

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.53 [2.19, 2.91] 1.5e-37 5369
15 years 0.01 1.59 [1.43, 1.77] 1.7e-17 2182
5 years 0.00 3.08 [2.81, 3.37] <1e-100 1492
1 year 0.00 6.49 [5.75, 7.32] <1e-100 651

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_POLYARTHROPATHIES – Polyarthropathies
GWS hits: 18

Survival analyses between endpoints

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Plot

before Polyarthropathies
after Polyarthropathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Polyarthropathies

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Endpoint not on priority list, no data to show.