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Felty syndrome

DOID EFO MESH SNOMED Endpoint Browser PheWeb

FELTY

Felty's syndrome: Felty syndrome (FS), also known as ''super rheumatoid'' disease, is a severe form of rheumatoid arthritis (RA), characterized by a triad of RA, splenomegaly and neutropenia, resulting in susceptibility to bacterial infections.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M05.0
Hospital discharge: ICD-9 7141
Hospital discharge: ICD-8 71210
Cause of death: ICD-10 M05.0
Cause of death: ICD-9 7141
Cause of death: ICD-8 71210

2 out of 7 registries used, show all original rules.

165

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Check minimum number of events None

165

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Include endpoints None

165

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Remove individuals based on genotype QC

160

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FELTY

Control definitions

Control exclude RHEUMA_SEROPOS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M05
Name in latin Syndroma Felty

Summary Statistics

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Key figures

All Female Male
Number of individuals 160 117 43
Unadjusted prevalence (%) 0.04 0.05 0.02
Mean age at first event (years) 57.92 57.85 58.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FELTY – Felty syndrome
GWS hits: 2

Survival analyses between endpoints

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Plot

before Felty syndrome
after Felty syndrome

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Felty syndrome

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Endpoint not on priority list, no data to show.