Felty syndrome

FELTY

Felty's syndrome: Felty syndrome (FS), also known as ''super rheumatoid'' disease, is a severe form of rheumatoid arthritis (RA), characterized by a triad of RA, splenomegaly and neutropenia, resulting in susceptibility to bacterial infections.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M05.0
Hospital discharge: ICD-9 7141
Hospital discharge: ICD-8 71210
Cause of death: ICD-10 M05.0
Cause of death: ICD-9 7141
Cause of death: ICD-8 71210

2 out of 7 registries used, show all original rules.

165

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Check minimum number of events None

165

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Include endpoints None

165

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Remove individuals based on genotype QC

160

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FELTY

Control definitions

Control exclude RHEUMA_SEROPOS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M05
Name in latin Syndroma Felty

Summary Statistics

Key figures

All Female Male
Number of individuals 160 117 43
Unadjusted prevalence (%) 0.04 0.05 0.02
Mean age at first event (years) 57.92 57.85 58.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: FELTY – Felty syndrome
GWS hits: 2

Survival analyses between endpoints

Plot

before Felty syndrome
after Felty syndrome

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Felty syndrome

Endpoint not on priority list, no data to show.