Nerve, nerve root and plexus disorders

G6_NERPLEX

peripheral nervous system disease: A disease involving the peripheral nervous system.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G50-G59, G53.0*B02.20, G53.0*B02.21
Cause of death: ICD-10 G50-G59, G53.0*B02.20, G53.0*B02.21

2 out of 7 registries used, show all original rules.

47068

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Check minimum number of events None

47068

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Remove individuals based on genotype QC

51643

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G6_NERPLEX

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 51643 31850 19793
Unadjusted prevalence (%) 12.54 13.83 10.89
Mean age at first event (years) 51.94 50.48 54.29

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.76 [1.55, 2.00] 4.1e-18 4953
15 years 0.01 1.31 [1.18, 1.45] 2.1e-7 2224
5 years 0.00 2.06 [1.88, 2.27] 2.9e-50 1070
1 year 0.00 3.60 [3.14, 4.14] 9.3e-73 354

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_NERPLEX – Nerve, nerve root and plexus disorders
GWS hits: 11

Survival analyses between endpoints

Plot

before Nerve, nerve root and plexus disorders
after Nerve, nerve root and plexus disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nerve, nerve root and plexus disorders

Endpoint not on priority list, no data to show.