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Other and unspecified mononeuropathies of lower limb

DOID EFO MESH SNOMED Endpoint Browser PheWeb

G6_MONOLOWOTHUNS

mononeuropathy: Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G57.8, G57.9
Hospital discharge: ICD-9 355[7-8]
Cause of death: ICD-10 G57.8, G57.9
Cause of death: ICD-9 355[7-8]

2 out of 7 registries used, show all original rules.

865

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Check minimum number of events None

865

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Include endpoints None

865

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Remove individuals based on genotype QC

842

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G6_MONOLOWOTHUNS

Control definitions

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 842 589 253
Unadjusted prevalence (%) 0.20 0.26 0.14
Mean age at first event (years) 51.39 50.49 53.49

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.83 [0.41, 1.65] 5.9e-1 59
15 years 0.01 0.76 [0.38, 1.52] 4.4e-1 28
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_MONOLOWOTHUNS – Other and unspecified mononeuropathies of lower limb
GWS hits:

Survival analyses between endpoints

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Plot

before Other and unspecified mononeuropathies of lower limb
after Other and unspecified mononeuropathies of lower limb

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Drugs most likely to be purchased after Other and unspecified mononeuropathies of lower limb

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Endpoint not on priority list, no data to show.