Other and unspecified mononeuropathies, also in other diseases

G6_MONOOTHUNS

mononeuropathy: Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions.

Endpoint definition

FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G58.8, G58.9, G59*
Hospital discharge: ICD-9 3559
Hospital discharge: ICD-8 35708
Cause of death: ICD-10 G58.8, G58.9, G59*
Cause of death: ICD-9 3559
Cause of death: ICD-8 35708

2 out of 7 registries used, show all original rules.

954

diagram downward connector

Check minimum number of events None

954

diagram downward connector

Include endpoints None

954

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

925

diagram downward connector
G6_MONOOTHUNS

Control definitions

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 925 522 403
Unadjusted prevalence (%) 0.22 0.23 0.22
Mean age at first event (years) 47.62 45.40 50.49

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.70 [0.81, 3.56] 1.6e-1 130
15 years 0.01 1.11 [0.58, 2.13] 7.4e-1 50
5 years 0.00 2.50 [1.47, 4.26] 7.7e-4 33
1 year 0.00 6.16 [3.24, 11.71] 2.9e-8 15

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_MONOOTHUNS – Other and unspecified mononeuropathies, also in other diseases
GWS hits: 1

Survival analyses between endpoints

Plot

before Other and unspecified mononeuropathies, also in other diseases
after Other and unspecified mononeuropathies, also in other diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified mononeuropathies, also in other diseases

Endpoint not on priority list, no data to show.