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Other and unspecified mononeuropathies, also in other diseases

DOID EFO MESH SNOMED Endpoint Browser PheWeb

G6_MONOOTHUNS

mononeuropathy: Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G58.8, G58.9, G59*
Hospital discharge: ICD-9 3559
Hospital discharge: ICD-8 35708
Cause of death: ICD-10 G58.8, G58.9, G59*
Cause of death: ICD-9 3559
Cause of death: ICD-8 35708

2 out of 7 registries used, show all original rules.

954

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Check minimum number of events None

954

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Include endpoints None

954

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Remove individuals based on genotype QC

925

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G6_MONOOTHUNS

Control definitions

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 925 522 403
Unadjusted prevalence (%) 0.22 0.23 0.22
Mean age at first event (years) 47.62 45.40 50.49

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.70 [0.81, 3.56] 1.6e-1 130
15 years 0.01 1.11 [0.58, 2.13] 7.4e-1 50
5 years 0.00 2.50 [1.47, 4.26] 7.7e-4 33
1 year 0.00 6.16 [3.24, 11.71] 2.9e-8 15

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_MONOOTHUNS – Other and unspecified mononeuropathies, also in other diseases
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other and unspecified mononeuropathies, also in other diseases
after Other and unspecified mononeuropathies, also in other diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified mononeuropathies, also in other diseases

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Endpoint not on priority list, no data to show.