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Other and unspecified mononeuropathies of upper limb

DOID EFO MESH SNOMED Endpoint Browser PheWeb

G6_MONONPOTHUS

mononeuropathy: Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G56.8, G56.9
Hospital discharge: ICD-9 354[8-9]
Cause of death: ICD-10 G56.8, G56.9
Cause of death: ICD-9 354[8-9]

2 out of 7 registries used, show all original rules.

909

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Check minimum number of events None

909

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Include endpoints None

909

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Remove individuals based on genotype QC

879

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G6_MONONPOTHUS

Control definitions

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 879 487 392
Unadjusted prevalence (%) 0.21 0.21 0.22
Mean age at first event (years) 47.37 45.82 49.29

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.82 [1.55, 5.14] 6.9e-4 65
15 years 0.02 2.32 [1.42, 3.79] 8.1e-4 31
5 years 0.00 2.30 [1.06, 4.99] 3.4e-2 11
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_MONONPOTHUS – Other and unspecified mononeuropathies of upper limb
GWS hits:

Survival analyses between endpoints

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Plot

before Other and unspecified mononeuropathies of upper limb
after Other and unspecified mononeuropathies of upper limb

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Drugs most likely to be purchased after Other and unspecified mononeuropathies of upper limb

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Endpoint not on priority list, no data to show.