Causalgia

G6_CAUSALGIA

causalgia: Complex regional pain syndrome type 2 (CRPS2), or causalgia is a form of complex regional pain syndrome that develops after damage to a peripheral nerve and is characterized by spontaneous pain, allodynia and hyperalgesia , not necessarily limited to the territory of the injured nerve, as well as at some point, edema, changes in skin blood flow or sudomotor dysfunction in the pain area.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G56.4
Hospital discharge: ICD-9 3544
Cause of death: ICD-10 G56.4
Cause of death: ICD-9 3544

2 out of 7 registries used, show all original rules.

503

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Check minimum number of events None

503

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Include endpoints None

503

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Remove individuals based on genotype QC

487

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G6_CAUSALGIA

Control definitions

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G56
Name in latin Causalgia

Summary Statistics

Key figures

All Female Male
Number of individuals 487 343 144
Unadjusted prevalence (%) 0.12 0.15 0.08
Mean age at first event (years) 46.29 45.72 47.63

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_CAUSALGIA – Causalgia
GWS hits:

Survival analyses between endpoints

Plot

before Causalgia
after Causalgia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Causalgia

Endpoint not on priority list, no data to show.