Brachial plexus disorders

G6_BRACHPLE

brachial plexus neuropathy: Diseases of the cervical (and first thoracic) roots, nerve trunks, cords, and peripheral nerve components of the BRACHIAL PLEXUS. Clinical manifestations include regional pain, PARESTHESIA; MUSCLE WEAKNESS, and decreased sensation (HYPESTHESIA) in the upper extremity. These disorders may be associated with trauma (including BIRTH INJURIES); THORACIC OUTLET SYNDROME; NEOPLASMS; NEURITIS; RADIOTHERAPY; and other conditions. (From Adams et al., Principles of Neurology, 6th ed, pp1351-2)

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G54.0
Hospital discharge: ICD-9 3530
Cause of death: ICD-10 G54.0
Cause of death: ICD-9 3530

2 out of 7 registries used, show all original rules.

3163

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Check minimum number of events None

3163

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Include endpoints None

3163

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Remove individuals based on genotype QC

3058

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G6_BRACHPLE

Control definitions

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G54
Name in latin Morbositates plexus brachialis

Summary Statistics

Key figures

All Female Male
Number of individuals 3058 2211 847
Unadjusted prevalence (%) 0.74 0.96 0.47
Mean age at first event (years) 44.94 43.59 48.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.83 [0.88, 3.82] 1.1e-1 100
15 years 0.01 1.61 [0.86, 3.01] 1.4e-1 48
5 years 0.00 2.72 [1.47, 5.04] 1.4e-3 21
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_BRACHPLE – Brachial plexus disorders
GWS hits:

Survival analyses between endpoints

Plot

before Brachial plexus disorders
after Brachial plexus disorders

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Drugs most likely to be purchased after Brachial plexus disorders

Endpoint not on priority list, no data to show.