Osteoporosis with pathological fracture (FG)

OSTEOPOROSIS_FRACTURE_FG

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

1822

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OSTEOPOROSIS_FRACTURE_FG

Control definitions

Control exclude RHEUMA_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1822 1709 113
Unadjusted prevalence (%) 0.44 0.74 0.06
Mean age at first event (years) 70.95 71.33 65.20

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 4.60 [2.83, 7.48] 7.5e-10 362
15 years 0.01 1.73 [1.12, 2.69] 1.4e-2 118
5 years 0.01 4.93 [3.51, 6.92] 3.2e-20 156
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: OSTEOPOROSIS_FRACTURE_FG – Osteoporosis with pathological fracture (FG)
GWS hits: 2

Survival analyses between endpoints

Plot

before Osteoporosis with pathological fracture (FG)
after Osteoporosis with pathological fracture (FG)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Osteoporosis with pathological fracture (FG)

Endpoint not on priority list, no data to show.