Postmenopausal osteoporosis with pathological fracture

OSTPOPATFRCTURE_POSTEMENO

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule

Sex only females

239906

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Check conditions None

239906

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M80.0
Cause of death: ICD-10 M80.0

2 out of 7 registries used, show all original rules.

1539

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Check minimum number of events None

1539

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Include endpoints None

1539

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Remove individuals based on genotype QC

1486

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OSTPOPATFRCTURE_POSTEMENO

Control definitions

Control exclude OSTEOPOROSIS_FRACTURE_FG

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M80
Name in latin Osteoporosis postmenopausalis cum fractura pathologica

Summary Statistics

Key figures

All Female Male
Number of individuals 1486 1486 -
Unadjusted prevalence (%) 0.36 0.65 -
Mean age at first event (years) 72.37 72.37 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.07 [1.53, 6.15] 1.6e-3 305
15 years 0.01 1.05 [0.55, 2.01] 8.8e-1 96
5 years 0.01 3.05 [2.00, 4.66] 2.3e-7 136
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: OSTPOPATFRCTURE_POSTEMENO – Postmenopausal osteoporosis with pathological fracture
GWS hits: 2

Survival analyses between endpoints

Plot

before Postmenopausal osteoporosis with pathological fracture
after Postmenopausal osteoporosis with pathological fracture

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Drugs most likely to be purchased after Postmenopausal osteoporosis with pathological fracture

Endpoint not on priority list, no data to show.