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Reactive arthropathies

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_REACTARTH

reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M02, M03*
Hospital discharge: ICD-9 7111|7115|7118|713
Hospital discharge: ICD-8 71490
Cause of death: ICD-10 M02, M03*
Cause of death: ICD-9 7111|7115|7118|713
Cause of death: ICD-8 71490

2 out of 7 registries used, show all original rules.

3145

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Check minimum number of events None

3145

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Include endpoints None

3145

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Remove individuals based on genotype QC

3058

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M13_REACTARTH

Control definitions

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 3058 1687 1371
Unadjusted prevalence (%) 0.74 0.73 0.75
Mean age at first event (years) 43.70 42.02 45.76

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.75 [1.14, 2.69] 1.1e-2 275
15 years 0.01 1.27 [0.90, 1.81] 1.8e-1 112
5 years 0.00 2.06 [1.40, 3.03] 2.2e-4 52
1 year 0.00 2.42 [1.27, 4.62] 7.4e-3 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_REACTARTH – Reactive arthropathies
GWS hits: 1

Survival analyses between endpoints

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Plot

before Reactive arthropathies
after Reactive arthropathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Reactive arthropathies

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Endpoint not on priority list, no data to show.