Arthrosis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_ARTHROSIS

Hemarthrosis: Bleeding into the joints. It may arise from trauma or spontaneously in patients with hemophilia.

Endpoint definition

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FinnGen phenotype data

429209 individuals

Apply sex-specific rule None

429209

Check conditions None

429209

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M15-M19

Cause of death: ICD-10 M15-M19

2 out of 7 registries used, show all original rules.

80507

Check minimum number of events None

80507

Include endpoints

M13_ARTHROSIS_POLY

M13_ARTHTROSIS_COX

M13_ARTHROSIS_KNEE

M13_ARTHROSIS_OTH

82967

Remove individuals based on genotype QC

80596

M13_ARTHROSIS

Control definitions

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

NAME	M13_ARTHROSIS
CONTROL_EXCLUDE	M13_ARTHROPATHIES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	M13_ARTHROSIS_POLY\|M13_ARTHTROSIS_COX\|M13_ARTHROSIS_KNEE\|M13_ARTHROSIS_OTH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M1[5-9]
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M1[5-9]
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Arthrosis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	80596	46659	33937
Unadjusted prevalence (%)	19.56	20.27	18.67
Mean age at first event (years)	59.24	59.01	59.55

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.35 [1.20, 1.51]	2.4e-7	9252
15 years	0.01	1.04 [0.95, 1.13]	3.9e-1	4474
5 years	0.00	1.52 [1.40, 1.64]	3.8e-25	1929
1 year	0.00	2.02 [1.78, 2.28]	7.0e-29	477

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_ARTHROSIS – Arthrosis
GWS hits: 76

Survival analyses between endpoints

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Plot

before Arthrosis
after Arthrosis

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Table

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Drugs most likely to be purchased after Arthrosis

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Endpoint not on priority list, no data to show.

≡ Risteys

R10

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R6

R5

R4

R3