hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I10-I15, I67.4
Hospital discharge: ICD-9 4019X|4029A|4029B|4039A|4040A|4059A|4059B|4372A|4059X
Hospital discharge: ICD-8 400|401|402|403|404
Cause of death: ICD-10 I10-I15, I67.4
Cause of death: ICD-9 4019X|4029A|4029B|4039A|4040A|4059A|4059B|4372A|4059X
Cause of death: ICD-8 400|401|402|403|404
KELA reimbursements: KELA codes 205

3 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude I9_HYPERTENSION

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 122993 58214 64779
Unadjusted prevalence (%) 29.85 25.28 35.64
Mean age at first event (years) 57.24 56.99 57.47


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.28 [2.12, 2.44] <1e-100 24433
15 years 0.01 1.54 [1.44, 1.64] 2.3e-39 10191
5 years 0.00 2.32 [2.18, 2.47] <1e-100 5090
1 year 0.00 6.61 [6.02, 7.26] <1e-100 2720

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: I9_HYPTENS – Hypertension
GWS hits: 301

Survival analyses between endpoints


before Hypertension
after Hypertension

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Drugs most likely to be purchased after Hypertension

Endpoint not on priority list, no data to show.