Hypertension, essential


No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I10
Hospital discharge: ICD-9 4039A|4019X
Hospital discharge: ICD-8 401|402|403|404
Cause of death: ICD-10 I10
Cause of death: ICD-9 4039A|4019X
Cause of death: ICD-8 401|402|403|404

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude I9_HYPERTENSION

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I10-I15
Name in latin Hypertensio essentialis (primaria)

Summary Statistics

Key figures

All Female Male
Number of individuals 102862 49558 53304
Unadjusted prevalence (%) 24.97 21.52 29.33
Mean age at first event (years) 63.29 62.84 63.71


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.46 [3.20, 3.75] <1e-100 20086
15 years 0.01 2.07 [1.93, 2.23] 4.9e-89 8268
5 years 0.01 3.54 [3.34, 3.76] <1e-100 5798
1 year 0.00 11.32 [10.40, 12.32] <1e-100 3819

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: I9_HYPTENSESS – Hypertension, essential
GWS hits: 224

Survival analyses between endpoints


before Hypertension, essential
after Hypertension, essential

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertension, essential