Hypertension, essential

I9_HYPTENSESS

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I10
Hospital discharge: ICD-9 4039A|4019X
Hospital discharge: ICD-8 401|402|403|404
Cause of death: ICD-10 I10
Cause of death: ICD-9 4039A|4019X
Cause of death: ICD-8 401|402|403|404

2 out of 7 registries used, show all original rules.

106137

diagram downward connector

Check minimum number of events None

106137

diagram downward connector

Include endpoints None

106137

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

102862

diagram downward connector
I9_HYPTENSESS

Control definitions

Control exclude I9_HYPERTENSION

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I10-I15
Name in latin Hypertensio essentialis (primaria)

Summary Statistics

Key figures

All Female Male
Number of individuals 102862 49558 53304
Unadjusted prevalence (%) 24.97 21.52 29.33
Mean age at first event (years) 63.29 62.84 63.71

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.46 [3.20, 3.75] <1e-100 20086
15 years 0.01 2.07 [1.93, 2.23] 4.9e-89 8268
5 years 0.01 3.54 [3.34, 3.76] <1e-100 5798
1 year 0.00 11.32 [10.40, 12.32] <1e-100 3819

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_HYPTENSESS – Hypertension, essential
GWS hits: 224

Survival analyses between endpoints

Plot

before Hypertension, essential
after Hypertension, essential

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertension, essential