Cardiovascular diseases (excluding rheumatic etc)


cardiovascular disease: A disease involving the cardiovascular system.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Remove individuals based on genotype QC


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Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 201525 96413 105112
Unadjusted prevalence (%) 48.92 41.87 57.84
Mean age at first event (years) 53.48 51.06 55.69


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.50 [4.24, 4.78] <1e-100 39661
15 years 0.01 3.17 [2.95, 3.40] <1e-100 16313
5 years 0.01 4.53 [4.18, 4.91] <1e-100 7129
1 year 0.00 20.51 [17.72, 23.75] <1e-100 5036

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: FG_CVD – Cardiovascular diseases (excluding rheumatic etc)
GWS hits: 87

Survival analyses between endpoints


before Cardiovascular diseases (excluding rheumatic etc)
after Cardiovascular diseases (excluding rheumatic etc)

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Drugs most likely to be purchased after Cardiovascular diseases (excluding rheumatic etc)

Endpoint not on priority list, no data to show.