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Cardiovascular diseases (excluding rheumatic etc)

DOID EFO MESH SNOMED Endpoint Browser PheWeb

FG_CVD

cardiovascular disease: A disease involving the cardiovascular system.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

208045

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Remove individuals based on genotype QC

201525

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FG_CVD

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 201525 96413 105112
Unadjusted prevalence (%) 48.92 41.87 57.84
Mean age at first event (years) 53.48 51.06 55.69

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.50 [4.24, 4.78] <1e-100 39661
15 years 0.01 3.17 [2.95, 3.40] <1e-100 16313
5 years 0.01 4.53 [4.18, 4.91] <1e-100 7129
1 year 0.00 20.51 [17.72, 23.75] <1e-100 5036

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FG_CVD – Cardiovascular diseases (excluding rheumatic etc)
GWS hits: 87

Survival analyses between endpoints

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Plot

before Cardiovascular diseases (excluding rheumatic etc)
after Cardiovascular diseases (excluding rheumatic etc)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cardiovascular diseases (excluding rheumatic etc)

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Endpoint not on priority list, no data to show.