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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Hypertensive heart and/or renal disease

I9_HYPTENSHR

nephrosclerosis: Hardening of the walls of the small arteries and arterioles (small arteries that convey blood from arteries to the even smaller capillaries) of the kidney. This condition is caused by hypertension (high blood pressure)

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I11, I12, I13
Hospital discharge: ICD-9 4029A|4029B|4039A|4040A
Hospital discharge: ICD-8 40299|40399|40499
Cause of death: ICD-10 I11, I12, I13
Cause of death: ICD-9 4029A|4029B|4039A|4040A
Cause of death: ICD-8 40299|40399|40499

2 out of 7 registries used, show all original rules.

10862

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Check minimum number of events None

10862

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Include endpoints

10862

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Remove individuals based on genotype QC

10482

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I9_HYPTENSHR

Control definitions

Control exclude I9_HYPERTENSION

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 10482 4078 6404
Unadjusted prevalence (%) 2.54 1.77 3.52
Mean age at first event (years) 67.11 68.79 66.05

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: I9_HYPTENSHR – Hypertensive heart and/or renal disease
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Hypertensive heart and/or renal disease

Endpoint not on priority list, no data to show.