≡ Risteys
R10

Documentation Changelog GitHub Contact & Feedback

Hypertensive Renal Disease

DOID EFO MESH SNOMED Endpoint Browser PheWeb

I9_HYPTENSRD

nephrosclerosis: Hardening of the walls of the small arteries and arterioles (small arteries that convey blood from arteries to the even smaller capillaries) of the kidney. This condition is caused by hypertension (high blood pressure)

Endpoint definition

↥
FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I12
Hospital discharge: ICD-9 4039A
Hospital discharge: ICD-8 40399
Cause of death: ICD-10 I12
Cause of death: ICD-9 4039A
Cause of death: ICD-8 40399

2 out of 7 registries used, show all original rules.

1153

diagram downward connector

Check minimum number of events None

1153

diagram downward connector

Include endpoints None

1153

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

1115

diagram downward connector
I9_HYPTENSRD

Control definitions

Control exclude I9_HYPERTENSION

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I10-I15
Name in latin Morbus hypertensivus renalis

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 1115 350 765
Unadjusted prevalence (%) 0.27 0.15 0.42
Mean age at first event (years) 62.46 59.62 63.76

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.14 7.15 [5.38, 9.49] 4.0e-42 424
15 years 0.02 2.37 [1.78, 3.17] 4.7e-9 122
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: I9_HYPTENSRD – Hypertensive Renal Disease
GWS hits: 1

Survival analyses between endpoints

↥

Plot

before Hypertensive Renal Disease
after Hypertensive Renal Disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertensive Renal Disease

↥

Endpoint not on priority list, no data to show.