Diseases of arteries, arterioles and capillaries (FINNGEN)

DOID EFO MESH SNOMED Endpoint Browser PheWeb

FG_DOAAC

vascular disease: A non-neoplastic or neoplastic disorder affecting the arteries, veins, or lymphatic vessels. Examples include vasculitis, thrombophlebitis, arteriosclerosis, lymphedema, hemangioma, and angiosarcoma.

Endpoint definition

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FinnGen phenotype data

429209 individuals

Apply sex-specific rule None

429209

Check conditions None

429209

Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

Check minimum number of events None

Include endpoints

I9_ATHSCLE

I9_AORTDIS

I9_AORTANEUR

I9_OTHANEUR

I9_ARTEMBTHR

I9_ARTEMBTHRLOW

I9_EMBTHROAOR

24912

Remove individuals based on genotype QC

24176

FG_DOAAC

Control definitions

Control exclude FG_CVD

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

NAME	FG_DOAAC
CONTROL_EXCLUDE	FG_CVD
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	I9_ATHSCLE\|I9_AORTDIS\|I9_AORTANEUR\|I9_OTHANEUR\|I9_ARTEMBTHR\|I9_ARTEMBTHRLOW\|I9_EMBTHROAOR
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

No data for upset plot.

No data for upset table.

Similar endpoints

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List of similar endpoints to Diseases of arteries, arterioles and capillaries (FINNGEN) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	24176	6529	17647
Unadjusted prevalence (%)	5.87	2.84	9.71
Mean age at first event (years)	67.51	67.19	67.63

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.11	4.99 [4.46, 5.57]	<1e-100	9324
15 years	0.02	2.59 [2.37, 2.84]	9.4e-97	3616
5 years	0.01	4.53 [4.20, 4.87]	<1e-100	2810
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FG_DOAAC – Diseases of arteries, arterioles and capillaries (FINNGEN)
GWS hits: 29

Survival analyses between endpoints

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Plot

before Diseases of arteries, arterioles and capillaries (FINNGEN)
after Diseases of arteries, arterioles and capillaries (FINNGEN)

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Diseases of arteries, arterioles and capillaries (FINNGEN)

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Endpoint not on priority list, no data to show.

≡ Risteys

R10

R9

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R5

R4

R3