Pulmonary embolism

I9_PULMEMB

pulmonary embolism: The obstruction of the pulmonary artery or one of its branches by an embolus, sometimes associated with infarction of the lung.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I26
Hospital discharge: ICD-9 415
Hospital discharge: ICD-8 450
Cause of death: ICD-10 I26
Cause of death: ICD-9 415
Cause of death: ICD-8 450

2 out of 7 registries used, show all original rules.

10371

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Check minimum number of events None

10371

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Include endpoints None

10371

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Remove individuals based on genotype QC

10045

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I9_PULMEMB

Control definitions

Control exclude I9_PULMHEART

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I26-I28
Name in latin Embolia pulmonalis

Summary Statistics

Key figures

All Female Male
Number of individuals 10045 5047 4998
Unadjusted prevalence (%) 2.44 2.19 2.75
Mean age at first event (years) 63.13 61.32 64.95

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.15 7.38 [6.14, 8.87] 2.0e-100 3128
15 years 0.01 1.95 [1.68, 2.28] 9.8e-18 610
5 years 0.01 6.18 [5.44, 7.02] <1e-100 799
1 year 0.01 47.49 [42.09, 53.58] <1e-100 1550

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_PULMEMB – Pulmonary embolism
GWS hits: 18

Survival analyses between endpoints

Plot

before Pulmonary embolism
after Pulmonary embolism

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Pulmonary embolism