Myeloproliferative diseases (CML excluded)

MYELOPROF_NONCML

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

not CML

428936

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

2043

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MYELOPROF_NONCML

Control definitions

Control conditions not CML

Extra metadata

First used in FinnGen datafreeze DF2, additional

Summary Statistics

Key figures

All Female Male
Number of individuals 2043 1055 988
Unadjusted prevalence (%) 0.50 0.46 0.54
Mean age at first event (years) 61.73 60.67 62.86

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.08 [2.22, 7.50] 5.7e-6 447
15 years 0.02 2.59 [1.70, 3.95] 9.9e-6 220
5 years 0.00 3.40 [2.52, 4.59] 1.2e-15 114
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: MYELOPROF_NONCML – Myeloproliferative diseases (CML excluded)
GWS hits: 18

Survival analyses between endpoints

Plot

before Myeloproliferative diseases (CML excluded)
after Myeloproliferative diseases (CML excluded)

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Drugs most likely to be purchased after Myeloproliferative diseases (CML excluded)

Endpoint not on priority list, no data to show.