Temporal arteritis

M13_TEMPARTERIT

temporal arteritis: Giant cell arteritis (GCA) is a large vessel vasculitis predominantly involving the arteries originating from the aortic arch and especially the extracranial branches of the carotid arteries.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M31.5
Cause of death: ICD-10 M31.5

2 out of 7 registries used, show all original rules.

979

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Check minimum number of events None

979

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Include endpoints None

979

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Remove individuals based on genotype QC

958

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M13_TEMPARTERIT

Control definitions

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 5
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Arteritis gigantocellularis cum polymyalgia reumatica

Summary Statistics

Key figures

All Female Male
Number of individuals 958 584 374
Unadjusted prevalence (%) 0.23 0.25 0.21
Mean age at first event (years) 68.26 67.51 69.44

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.12 5.80 [4.08, 8.25] 1.4e-22 179
15 years 0.02 2.55 [1.77, 3.67] 5.0e-7 72
5 years 0.01 4.87 [3.36, 7.05] 6.2e-17 67
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_TEMPARTERIT – Temporal arteritis
GWS hits:

Survival analyses between endpoints

Plot

before Temporal arteritis
after Temporal arteritis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Temporal arteritis

Endpoint not on priority list, no data to show.