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Disorders of muscles

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_MUSCLE

myositis: An inflammatory disease involving a pathogenic inflammatory response in the muscle tissue.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M60-M63
Cause of death: ICD-10 M60-M63

2 out of 7 registries used, show all original rules.

2855

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Check minimum number of events None

2855

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Include endpoints

3450

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Remove individuals based on genotype QC

3322

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M13_MUSCLE

Control definitions

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 3322 1783 1539
Unadjusted prevalence (%) 0.81 0.77 0.85
Mean age at first event (years) 49.62 47.96 51.55

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.96 [2.01, 4.36] 4.4e-8 357
15 years 0.01 1.59 [1.10, 2.31] 1.4e-2 124
5 years 0.00 3.12 [2.23, 4.36] 2.6e-11 93
1 year 0.00 10.57 [7.07, 15.80] 1.6e-30 73

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MUSCLE – Disorders of muscles
GWS hits: 1

Survival analyses between endpoints

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Plot

before Disorders of muscles
after Disorders of muscles

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of muscles

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Endpoint not on priority list, no data to show.