Other specified disorders of muscle

DOID EFO MESH SNOMED Endpoint Browser PheWeb

M13_MUSCLEDISNAS

myopathy: a disease of the muscle in which the muscle fibers do not function properly. This results in muscular weakness.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M62.8, M62.9

Hospital discharge: ICD-9 728[8-9]

Hospital discharge: ICD-8 733

Hospital discharge: excluded ICD-8 733|777[0-1]|73390

Cause of death: ICD-10 M62.8, M62.9

Cause of death: ICD-9 728[8-9]

Cause of death: ICD-8 733

Cause of death: excluded ICD-8 733|777[0-1]|73390

2 out of 7 registries used, show all original rules.

909

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Check minimum number of events None

909

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Include endpoints None

909

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Remove individuals based on genotype QC

882

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M13_MUSCLEDISNAS

Control definitions

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

NAME	M13_MUSCLEDISNAS
CONTROL_EXCLUDE	M13_SOFTTISSUE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M62[8-9]
HD_ICD_9	728[8-9]
HD_ICD_8	733
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL	733\|777[0-1]\|73390
COD_MAINONLY
COD_ICD_10	M62[8-9]
COD_ICD_9	728[8-9]
COD_ICD_8	733
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL	733\|777[0-1]\|73390
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Other specified disorders of muscle based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	882	448	434
Unadjusted prevalence (%)	0.21	0.19	0.24
Mean age at first event (years)	44.43	44.63	44.22

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.09	4.70 [2.55, 8.65]	6.7e-7	126
15 years	0.02	2.03 [1.22, 3.36]	6.0e-3	33
5 years	0.00	2.73 [1.36, 5.51]	4.9e-3	19
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MUSCLEDISNAS – Other specified disorders of muscle
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other specified disorders of muscle
after Other specified disorders of muscle

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Table

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Drugs most likely to be purchased after Other specified disorders of muscle

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Endpoint not on priority list, no data to show.