Myositis

M13_MYOSITIS

myositis: An inflammatory disease involving a pathogenic inflammatory response in the muscle tissue.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M60
Hospital discharge: ICD-9 7280
Hospital discharge: ICD-8 732
Cause of death: ICD-10 M60
Cause of death: ICD-9 7280
Cause of death: ICD-8 732

2 out of 7 registries used, show all original rules.

790

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Check minimum number of events None

790

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Include endpoints None

790

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Remove individuals based on genotype QC

759

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M13_MYOSITIS

Control definitions

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M60-M63
Name in latin Myositis

Summary Statistics

Key figures

All Female Male
Number of individuals 759 394 365
Unadjusted prevalence (%) 0.18 0.17 0.20
Mean age at first event (years) 52.58 50.46 54.88

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 3.97 [2.43, 6.47] 3.3e-8 88
15 years 0.02 2.21 [1.37, 3.57] 1.2e-3 36
5 years 0.01 4.51 [2.76, 7.38] 1.9e-9 26
1 year 0.00 10.40 [5.40, 20.04] 2.6e-12 13

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_MYOSITIS – Myositis
GWS hits: 1

Survival analyses between endpoints

Plot

before Myositis
after Myositis

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Drugs most likely to be purchased after Myositis

Endpoint not on priority list, no data to show.