psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L40
Cause of death: ICD-10 L40

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Remove individuals based on genotype QC


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Control definitions

Control exclude L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L40-L45
Name in latin Psoriasis

Summary Statistics

Key figures

All Female Male
Number of individuals 10312 5400 4912
Unadjusted prevalence (%) 2.50 2.35 2.70
Mean age at first event (years) 49.67 48.56 50.90


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.27 [1.84, 2.80] 3.0e-14 1016
15 years 0.01 1.65 [1.34, 2.04] 3.1e-6 503
5 years 0.00 2.15 [1.75, 2.64] 1.8e-13 200
1 year 0.00 3.13 [2.31, 4.25] 2.1e-13 54

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: L12_PSORIASIS – Psoriasis
GWS hits: 41

Survival analyses between endpoints


before Psoriasis
after Psoriasis

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