Generalized pustular psoriasis

DOID EFO MESH Endpoint Browser PheWeb

L12_PSORI_PUSTGEN

impetigo herpetiformis: An impetigo that is characterized as a form of severe pustular psoriasis occurring in pregnancy.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L40.1

Hospital discharge: ICD-9 6961B

Hospital discharge: ICD-8 69610

Cause of death: ICD-10 L40.1

Cause of death: ICD-9 6961B

Cause of death: ICD-8 69610

2 out of 7 registries used, show all original rules.

105

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Check minimum number of events None

105

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Include endpoints None

105

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Remove individuals based on genotype QC

101

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L12_PSORI_PUSTGEN

Control definitions

Control exclude L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L40

Name in latin Psoriasis pustulosa generalisata

NAME	L12_PSORI_PUSTGEN
CONTROL_EXCLUDE	L12_PAPULOSQUAMOUS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L401
HD_ICD_9	6961B
HD_ICD_8	69610
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L401
COD_ICD_9	6961B
COD_ICD_8	69610
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Generalized pustular psoriasis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	101	52	49
Unadjusted prevalence (%)	0.02	0.02	0.03
Mean age at first event (years)	53.21	51.28	55.26

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_PSORI_PUSTGEN – Generalized pustular psoriasis
GWS hits:

Survival analyses between endpoints

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Plot

before Generalized pustular psoriasis
after Generalized pustular psoriasis

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Table

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Drugs most likely to be purchased after Generalized pustular psoriasis

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Endpoint not on priority list, no data to show.