Psoriasis vulgaris

L12_PSORI_VULG

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L40.0
Hospital discharge: ICD-9 6961A
Cause of death: ICD-10 L40.0
Cause of death: ICD-9 6961A
KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 L40.0

3 out of 7 registries used, show all original rules.

6672

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Check minimum number of events None

6672

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Include endpoints None

6672

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Remove individuals based on genotype QC

6408

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L12_PSORI_VULG

Control definitions

Control exclude L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L40
Name in latin Psoriasis vulgaris

Summary Statistics

Key figures

All Female Male
Number of individuals 6408 3061 3347
Unadjusted prevalence (%) 1.56 1.33 1.84
Mean age at first event (years) 50.87 49.09 52.50

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.00 [1.41, 2.84] 1.1e-4 662
15 years 0.01 1.49 [1.07, 2.08] 1.9e-2 325
5 years 0.00 2.32 [1.76, 3.06] 2.4e-9 150
1 year 0.00 3.09 [2.11, 4.52] 6.1e-9 38

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_PSORI_VULG – Psoriasis vulgaris
GWS hits: 28

Survival analyses between endpoints

Plot

before Psoriasis vulgaris
after Psoriasis vulgaris

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Psoriasis vulgaris

Endpoint not on priority list, no data to show.