All pneumoniae

J10_PNEUMONIA

pneumonia: An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

63377

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J10_PNEUMONIA

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 63377 26170 37207
Unadjusted prevalence (%) 15.38 11.37 20.47
Mean age at first event (years) 56.70 51.74 60.19

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.17 8.70 [8.00, 9.47] <1e-100 20575
15 years 0.02 3.30 [3.03, 3.61] <1e-100 4391
5 years 0.01 8.32 [7.75, 8.92] <1e-100 5899
1 year 0.01 44.20 [40.46, 48.29] <1e-100 9244

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: J10_PNEUMONIA – All pneumoniae
GWS hits: 6

Survival analyses between endpoints

Plot

before All pneumoniae
after All pneumoniae

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Drugs most likely to be purchased after All pneumoniae

Endpoint not on priority list, no data to show.