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Extrapyramidal and movement disorders

DOID EFO MESH SNOMED Endpoint Browser PheWeb

G6_XTRAPYR

basal ganglia disease: A disease involving the basal ganglia.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G20-G26
Cause of death: ICD-10 G20-G26

2 out of 7 registries used, show all original rules.

10566

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Check minimum number of events None

10566

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Include endpoints

12888

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Remove individuals based on genotype QC

12518

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G6_XTRAPYR

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 12518 6656 5862
Unadjusted prevalence (%) 3.04 2.89 3.23
Mean age at first event (years) 61.15 59.01 63.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.48 [2.85, 4.26] 3.6e-34 2238
15 years 0.01 2.01 [1.65, 2.44] 4.3e-12 1051
5 years 0.01 3.54 [3.07, 4.09] 9.8e-67 756
1 year 0.00 4.65 [3.86, 5.61] 2.1e-58 205

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_XTRAPYR – Extrapyramidal and movement disorders
GWS hits: 4

Survival analyses between endpoints

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Plot

before Extrapyramidal and movement disorders
after Extrapyramidal and movement disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Extrapyramidal and movement disorders

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Endpoint not on priority list, no data to show.