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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Secondary parkinsonism+Parkinsonism in other disease

G6_PARKSCND

postencephalitic Parkinson disease: Parkinsonism following encephalitis, historically seen as a sequella of encephalitis lethargica (Von Economo Encephalitis). The early age of onset, the rapid progression of symptoms followed by stabilization, and the presence of a variety of other neurological disorders (e.g., sociopathic behavior; TICS; MUSCLE SPASMS; oculogyric crises; hyperphagia; and bizarre movements) distinguish this condition from primary PARKINSON DISEASE. Pathologic features include neuronal loss and gliosis concentrated in the MESENCEPHALON; SUBTHALAMUS; and HYPOTHALAMUS. (From Adams et al., Principles of Neurology, 6th ed, p754)

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G21, G22*, G22*A52.1
Hospital discharge: ICD-9 3321
Hospital discharge: ICD-8 3420[8-9]
Cause of death: ICD-10 G21, G22*, G22*A52.1
Cause of death: ICD-9 3321
Cause of death: ICD-8 3420[8-9]

2 out of 7 registries used, show all original rules.

836

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Check minimum number of events None

836

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Include endpoints None

836

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Remove individuals based on genotype QC

807

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G6_PARKSCND

Control definitions

Control exclude G6_XTRAPYR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 807 331 476
Unadjusted prevalence (%) 0.20 0.14 0.26
Mean age at first event (years) 62.63 62.44 62.76

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: G6_PARKSCND – Secondary parkinsonism+Parkinsonism in other disease
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Secondary parkinsonism+Parkinsonism in other disease

Endpoint not on priority list, no data to show.