Other neurological diseases

DOID EFO MESH SNOMED Endpoint Browser PheWeb

G6_OTHNEU

nervous system disease: A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves.

Endpoint definition

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FinnGen phenotype data

429209 individuals

Apply sex-specific rule None

429209

Check conditions None

429209

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G90-G99

Cause of death: ICD-10 G90-G99

2 out of 7 registries used, show all original rules.

9633

Check minimum number of events None

9633

Include endpoints

G6_AUTONOM

G6_HYDROCEPH

G6_ENCEPHTOX

G6_CERCYST

G6_ANOXBRAINDAM

G6_BENINTRAHYP

G6_POSTVIRFAT

G6_ENCEPATH

G6_COMPBRAIN

G6_CEROEDEMA

G6_REYE

G6_DISBROTHUNS

G6_SPINOTH

G6_CNSOTH

G6_POSTOPNEURO

G6_NEUROOTH

G6_TIA

G6_VASCSYND

30939

Remove individuals based on genotype QC

29982

G6_OTHNEU

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	G6_OTHNEU
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	G6_AUTONOM\|G6_HYDROCEPH\|G6_ENCEPHTOX\|G6_CERCYST\|G6_ANOXBRAINDAM\|G6_BENINTRAHYP\|G6_POSTVIRFAT\|G6_ENCEPATH\|G6_COMPBRAIN\|G6_CEROEDEMA\|G6_REYE\|G6_DISBROTHUNS\|G6_SPINOTH\|G6_CNSOTH\|G6_POSTOPNEURO\|G6_NEUROOTH\|G6_TIA\|G6_VASCSYND
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G9
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G9
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Other neurological diseases based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	29982	14949	15033
Unadjusted prevalence (%)	7.28	6.49	8.27
Mean age at first event (years)	60.91	58.41	63.39

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	3.34 [2.92, 3.82]	4.6e-69	6478
15 years	0.01	1.90 [1.72, 2.10]	7.5e-37	2738
5 years	0.00	3.25 [3.00, 3.52]	<1e-100	1951
1 year	0.00	8.58 [7.73, 9.52]	<1e-100	1085

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_OTHNEU – Other neurological diseases
GWS hits: 2

Survival analyses between endpoints

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Plot

before Other neurological diseases
after Other neurological diseases

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Table

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Drugs most likely to be purchased after Other neurological diseases

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Endpoint not on priority list, no data to show.

≡ Risteys

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