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Other disorders of nervous system

DOID EFO MESH SNOMED Endpoint Browser PheWeb

G6_NEUROOTH

nervous system disease: A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G98, G99*
Cause of death: ICD-10 G98, G99*

2 out of 7 registries used, show all original rules.

1997

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Check minimum number of events None

1997

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Include endpoints None

1997

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Remove individuals based on genotype QC

1920

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G6_NEUROOTH

Control definitions

Control exclude G6_OTHNEU

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1920 944 976
Unadjusted prevalence (%) 0.47 0.41 0.54
Mean age at first event (years) 58.59 56.81 60.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 3.94 [2.83, 5.47] 3.1e-16 221
15 years 0.02 2.14 [1.52, 3.01] 1.2e-5 99
5 years 0.01 4.06 [2.87, 5.73] 1.9e-15 73
1 year 0.00 8.59 [5.49, 13.45] 5.1e-21 32

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_NEUROOTH – Other disorders of nervous system
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other disorders of nervous system
after Other disorders of nervous system

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Drugs most likely to be purchased after Other disorders of nervous system

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Endpoint not on priority list, no data to show.