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Transient ischemic attack

DOID EFO MESH SNOMED Endpoint Browser PheWeb

I9_TIA

transient ischemic attack: A brief attack (from a few minutes to an hour) of cerebral dysfunction of vascular origin, with no persistent neurological deficit.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G45
Hospital discharge: ICD-9 435
Hospital discharge: ICD-8 435
Hospital discharge: excluded ICD-10 G45.4
Cause of death: ICD-10 G45
Cause of death: ICD-9 435
Cause of death: ICD-8 435
Cause of death: excluded ICD-10 G45.4

2 out of 7 registries used, show all original rules.

20576

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Check minimum number of events None

20576

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Include endpoints None

20576

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Remove individuals based on genotype QC

19929

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I9_TIA

Control definitions

Control exclude I9_STR_EXH

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 G40-G47
Name in latin Ischaemia cerebri transitoria et syndomata cognata

Summary Statistics

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Key figures

All Female Male
Number of individuals 19929 9350 10579
Unadjusted prevalence (%) 4.84 4.06 5.82
Mean age at first event (years) 65.47 64.64 66.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.76 [2.35, 3.25] 5.0e-34 4612
15 years 0.01 1.62 [1.44, 1.82] 1.3e-15 2043
5 years 0.00 2.92 [2.65, 3.21] <1e-100 1464
1 year 0.00 5.45 [4.81, 6.18] <1e-100 573

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_TIA – Transient ischemic attack
GWS hits: 2

Survival analyses between endpoints

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Plot

before Transient ischemic attack
after Transient ischemic attack

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Transient ischemic attack

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Endpoint not on priority list, no data to show.