Autonomic disorders

G6_AUTONOM

autonomic nervous system disease: A disease involving the autonomic nervous system.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G90
Cause of death: ICD-10 G90

2 out of 7 registries used, show all original rules.

620

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Check minimum number of events None

620

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Remove individuals based on genotype QC

621

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G6_AUTONOM

Control definitions

Control exclude G6_OTHNEU

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G90-G99
Name in latin Morbositates systematis nervosi autonomici

Summary Statistics

Key figures

All Female Male
Number of individuals 621 336 285
Unadjusted prevalence (%) 0.15 0.15 0.16
Mean age at first event (years) 55.16 54.29 56.19

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.97 [0.75, 5.20] 1.7e-1 104
15 years 0.01 0.68 [0.26, 1.79] 4.4e-1 26
5 years 0.01 4.02 [1.91, 8.45] 2.5e-4 41
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_AUTONOM – Autonomic disorders
GWS hits: 1

Survival analyses between endpoints

Plot

before Autonomic disorders
after Autonomic disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Autonomic disorders

Endpoint not on priority list, no data to show.