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Ovarian dysfunction

DOID EFO MESH SNOMED Endpoint Browser PheWeb

E4_OVARDYS

ovarian dysfunction: The inability of the ovaries to function.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule

Sex only females

239906

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Check conditions None

239906

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E28
Cause of death: ICD-10 E28

2 out of 7 registries used, show all original rules.

1985

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Check minimum number of events None

1985

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Include endpoints

2451

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Remove individuals based on genotype QC

2309

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E4_OVARDYS

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E20-E35
Name in latin Dysfunctio ovarialis

Summary Statistics

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Key figures

All Female Male
Number of individuals 2309 2309 -
Unadjusted prevalence (%) 0.56 1.00 -
Mean age at first event (years) 30.57 30.57 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.76 [0.30, 1.93] 5.6e-1 42
15 years 0.00 0.52 [0.16, 1.69] 2.8e-1 16
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OVARDYS – Ovarian dysfunction
GWS hits: 6

Survival analyses between endpoints

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Plot

before Ovarian dysfunction
after Ovarian dysfunction

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ovarian dysfunction

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Endpoint not on priority list, no data to show.