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This is a non-core endpoint: only basic statistics are computed.

Ovarian dysfunction: estrogen excess

E4_ODESTRO

hyperestrogenism: ['Abnormally high level of estrogen. [ NICHD NCI ]']

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule

Sex only females

239906

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Check conditions None

239906

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E28.0#
Hospital discharge: ICD-9 2560
Hospital discharge: ICD-8 2560
Cause of death: ICD-10 E28.0#
Cause of death: ICD-9 2560
Cause of death: ICD-8 2560

2 out of 7 registries used, show all original rules.

41

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Check minimum number of events None

41

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Include endpoints None

41

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Remove individuals based on genotype QC

39

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E4_ODESTRO

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E28
Name in latin Hypersecretio oestrogenorum

Summary Statistics

Key figures

All Female Male
Number of individuals 39 39 -
Unadjusted prevalence (%) 0.01 0.02 -
Mean age at first event (years) 32.59 32.59 -

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: E4_ODESTRO – Ovarian dysfunction: estrogen excess
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Ovarian dysfunction: estrogen excess

Endpoint not on priority list, no data to show.