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Obesity

DOID EFO MESH SNOMED Endpoint Browser PheWeb

E4_OBESITY

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E66
Cause of death: ICD-10 E66

2 out of 7 registries used, show all original rules.

23960

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Check minimum number of events None

23960

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Include endpoints

24853

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Remove individuals based on genotype QC

23970

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E4_OBESITY

Control definitions

Control exclude E4_OBESITY_HYPER

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E65-E68
Name in latin Obesitas

Summary Statistics

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Key figures

All Female Male
Number of individuals 23970 15764 8206
Unadjusted prevalence (%) 5.82 6.85 4.52
Mean age at first event (years) 48.86 46.53 53.34

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 4.84 [4.10, 5.71] 2.6e-78 2022
15 years 0.02 2.81 [2.41, 3.27] 2.8e-40 869
5 years 0.01 4.43 [3.82, 5.14] 5.8e-87 491
1 year 0.00 15.52 [13.17, 18.30] <1e-100 327

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITY – Obesity
GWS hits: 55

Survival analyses between endpoints

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Plot

before Obesity
after Obesity

loading spinner Loading survival analyses plot