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Obesity, other/unspecified

DOID EFO MESH SNOMED Endpoint Browser PheWeb

E4_OBESITYNAS

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E66.8, E66.9
Hospital discharge: ICD-9 2780
Hospital discharge: ICD-8 27799
Cause of death: ICD-10 E66.8, E66.9
Cause of death: ICD-9 2780
Cause of death: ICD-8 27799

2 out of 7 registries used, show all original rules.

12738

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Check minimum number of events None

12738

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Include endpoints None

12738

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Remove individuals based on genotype QC

12288

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E4_OBESITYNAS

Control definitions

Control exclude E4_OBESITY

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 12288 8498 3790
Unadjusted prevalence (%) 2.98 3.69 2.09
Mean age at first event (years) 47.11 45.45 50.84

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.46 [2.55, 4.70] 2.0e-15 1122
15 years 0.02 2.14 [1.69, 2.72] 3.4e-10 456
5 years 0.01 3.76 [3.05, 4.63] 1.6e-35 248
1 year 0.00 15.72 [12.64, 19.56] <1e-100 195

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITYNAS – Obesity, other/unspecified
GWS hits: 19

Survival analyses between endpoints

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Plot

before Obesity, other/unspecified
after Obesity, other/unspecified

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Obesity, other/unspecified

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Endpoint not on priority list, no data to show.