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Extreme obesity with alveolar hypoventilation

DOID EFO MESH SNOMED Endpoint Browser PheWeb

E4_OBESITYXTRMALV

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E66.2
Hospital discharge: ICD-9 2788A
Cause of death: ICD-10 E66.2
Cause of death: ICD-9 2788A

2 out of 7 registries used, show all original rules.

1208

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Check minimum number of events None

1208

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Include endpoints None

1208

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Remove individuals based on genotype QC

1177

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E4_OBESITYXTRMALV

Control definitions

Control exclude E4_OBESITY

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E66
Name in latin Obesitas extrema cum hypoventilatione alveolari

Summary Statistics

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Key figures

All Female Male
Number of individuals 1177 661 516
Unadjusted prevalence (%) 0.29 0.29 0.28
Mean age at first event (years) 58.27 56.87 60.07

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.22 12.06 [7.60, 19.12] 3.8e-26 223
15 years 0.03 3.61 [2.18, 5.97] 5.9e-7 61
5 years 0.01 10.51 [6.47, 17.06] 1.7e-21 84
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITYXTRMALV – Extreme obesity with alveolar hypoventilation
GWS hits: 1

Survival analyses between endpoints

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Plot

before Extreme obesity with alveolar hypoventilation
after Extreme obesity with alveolar hypoventilation

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Drugs most likely to be purchased after Extreme obesity with alveolar hypoventilation

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Endpoint not on priority list, no data to show.