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Obesity due to excess calories

DOID EFO MESH SNOMED Endpoint Browser PheWeb

E4_OBESITYCAL

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E66.00, E66.01
Cause of death: ICD-10 E66.00, E66.01

2 out of 7 registries used, show all original rules.

17634

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Check minimum number of events None

17634

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Include endpoints None

17634

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Remove individuals based on genotype QC

16975

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E4_OBESITYCAL

Control definitions

Control exclude E4_OBESITY

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 16975 11030 5945
Unadjusted prevalence (%) 4.12 4.79 3.27
Mean age at first event (years) 50.00 47.39 54.85

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 3.99 [3.04, 5.23] 2.0e-23 1244
15 years 0.02 2.48 [2.00, 3.08] 1.8e-16 559
5 years 0.01 4.64 [3.82, 5.64] 1.4e-53 353
1 year 0.00 13.31 [10.72, 16.52] <1e-100 191

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITYCAL – Obesity due to excess calories
GWS hits: 27

Survival analyses between endpoints

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Plot

before Obesity due to excess calories
after Obesity due to excess calories

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Obesity due to excess calories

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Endpoint not on priority list, no data to show.