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Type 2 diabetes

E4_DM2

type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E11
Cause of death: ICD-10 E11
Medicine purchases: ATC A10B

3 out of 7 registries used, show all original rules.

72854

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Check minimum number of events

Min. number of events 3

72854

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Remove individuals based on genotype QC

71816

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E4_DM2

Control definitions

Control exclude E4_DIABETES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9
Parent code in ICD-10 E10-E14

Summary Statistics

Key figures

All Female Male
Number of individuals 71816 31907 39909
Unadjusted prevalence (%) 17.43 13.86 21.96
Mean age at first event (years) 58.60 57.22 59.71

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: E4_DM2 – Type 2 diabetes
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Type 2 diabetes

Endpoint not on priority list, no data to show.