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Certain disorders involving the immune mechanism

DOID EFO MESH SNOMED Endpoint Browser PheWeb

D3_IMMUNEMECHANISM

immune system disease: A disorder resulting from an abnormality in the immune system.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

6805

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Remove individuals based on genotype QC

6561

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D3_IMMUNEMECHANISM

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

No data for upset plot.

No data for upset table.

Similar endpoints

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List of similar endpoints to Certain disorders involving the immune mechanism based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 6561 3633 2928
Unadjusted prevalence (%) 1.59 1.58 1.61
Mean age at first event (years) 47.20 46.95 47.51

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.65 [1.13, 2.41] 9.8e-3 673
15 years 0.01 1.10 [0.76, 1.60] 6.2e-1 253
5 years 0.00 2.52 [1.85, 3.45] 6.7e-9 152
1 year 0.00 7.49 [5.39, 10.42] 4.3e-33 84

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_IMMUNEMECHANISM – Certain disorders involving the immune mechanism
GWS hits: 10

Survival analyses between endpoints

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Plot

before Certain disorders involving the immune mechanism
after Certain disorders involving the immune mechanism

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Drugs most likely to be purchased after Certain disorders involving the immune mechanism

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Endpoint not on priority list, no data to show.