Immunodeficiency associated with other major defects

MESH Endpoint Browser PheWeb

D3_IMMUDEFWITHMAJORDEF

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D82

Cause of death: ICD-10 D82

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints

D3_WISKOTTALDRICH

D3_DIGEORGE

D3_IMMUDEFSHORTLIMB

D3_IMMUDEFPOSTEBV

D3_IMMUDEFMAJORDEFNAS

78

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Remove individuals based on genotype QC

72

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D3_IMMUDEFWITHMAJORDEF

Control definitions

Control exclude D3_IMMUNEMECHANISM

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D80-D89

Name in latin Deficientia immunalis cum aliis defectibus majoribus

NAME	D3_IMMUDEFWITHMAJORDEF
CONTROL_EXCLUDE	D3_IMMUNEMECHANISM
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	D3_WISKOTTALDRICH\|D3_DIGEORGE\|D3_IMMUDEFSHORTLIMB\|D3_IMMUDEFPOSTEBV\|D3_HYPERIGESDR\|D3_IMMUDEFMAJORDEFNAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D82
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D82
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Immunodeficiency associated with other major defects based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	72	37	35
Unadjusted prevalence (%)	0.02	0.02	0.02
Mean age at first event (years)	40.87	38.46	43.43

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_IMMUDEFWITHMAJORDEF – Immunodeficiency associated with other major defects
GWS hits:

Survival analyses between endpoints

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Plot

before Immunodeficiency associated with other major defects
after Immunodeficiency associated with other major defects

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Table

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Drugs most likely to be purchased after Immunodeficiency associated with other major defects

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Endpoint not on priority list, no data to show.