Immunodeficiency with predominantly antibody defects

DOID MESH Endpoint Browser PheWeb

D3_IMMUDEFANTIBODY

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D80

Cause of death: ICD-10 D80

2 out of 7 registries used, show all original rules.

779

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Check minimum number of events None

779

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Include endpoints

D3_HEREDHYPOGAMMA

D3_NONHEREDHYPOGAMMA

D3_DEF_IIGA

D3_DEF_IGG

D3_DEF_IGM

D3_IMMUDEF_INCR_IGM

D3_AB_DEF_NORMHYPERIG

D3_TRANSHYPOGAMMAINFANT

D3_IMMUDEFANTIBODYNAS

800

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Remove individuals based on genotype QC

767

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D3_IMMUDEFANTIBODY

Control definitions

Control exclude D3_IMMUNEMECHANISM

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D80-D89

Name in latin Deficientia immunalis praecipue cum vitiis anticorporum

NAME	D3_IMMUDEFANTIBODY
CONTROL_EXCLUDE	D3_IMMUNEMECHANISM
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	D3_HEREDHYPOGAMMA\|D3_NONHEREDHYPOGAMMA\|D3_DEF_IIGA\|D3_DEF_IGG\|D3_DEF_IGM\|D3_IMMUDEF_INCR_IGM\|D3_AB_DEF_NORMHYPERIG\|D3_TRANSHYPOGAMMAINFANT\|D3_IMMUDEFANTIBODYNAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D80
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D80
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Immunodeficiency with predominantly antibody defects based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	767	507	260
Unadjusted prevalence (%)	0.19	0.22	0.14
Mean age at first event (years)	46.11	45.70	46.92

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_IMMUDEFANTIBODY – Immunodeficiency with predominantly antibody defects
GWS hits:

Survival analyses between endpoints

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Plot

before Immunodeficiency with predominantly antibody defects
after Immunodeficiency with predominantly antibody defects

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Table

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Drugs most likely to be purchased after Immunodeficiency with predominantly antibody defects

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Endpoint not on priority list, no data to show.