Obesity related asthma

ASTHMA_OBESITY

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

J10_ASTHMA

48366

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

11893

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Remove individuals based on genotype QC

11546

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ASTHMA_OBESITY

Control definitions

Control conditions not J10_ASTHMA

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 11546 6661 4885
Unadjusted prevalence (%) 2.80 2.89 2.69
Mean age at first event (years) 52.96 51.86 54.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.93 [1.47, 2.52] 1.7e-6 941
15 years 0.01 1.39 [1.09, 1.77] 8.8e-3 419
5 years 0.00 2.63 [2.11, 3.29] 1.8e-17 228
1 year 0.00 5.16 [3.89, 6.85] 5.2e-30 83

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ASTHMA_OBESITY – Obesity related asthma
GWS hits: 9

Survival analyses between endpoints

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Plot

before Obesity related asthma
after Obesity related asthma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Obesity related asthma

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Endpoint not on priority list, no data to show.