≡ Risteys
R10

Documentation Changelog GitHub Contact & Feedback

Chronic lower respiratory diseases

DOID EFO MESH SNOMED Endpoint Browser PheWeb

J10_LOWCHRON

lung disease: A disease involving the lung.

Endpoint definition

↥
FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J40-J47
Cause of death: ICD-10 J40-J47

2 out of 7 registries used, show all original rules.

59124

diagram downward connector

Check minimum number of events None

59124

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

76323

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

73877

diagram downward connector
J10_LOWCHRON

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 73877 39600 34277
Unadjusted prevalence (%) 17.93 17.20 18.86
Mean age at first event (years) 47.10 42.80 52.07

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.78 [2.54, 3.04] <1e-100 13368
15 years 0.01 1.87 [1.73, 2.01] 2.1e-59 5117
5 years 0.01 3.76 [3.52, 4.02] <1e-100 3629
1 year 0.00 11.47 [10.45, 12.60] <1e-100 2275

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: J10_LOWCHRON – Chronic lower respiratory diseases
GWS hits: 72

Survival analyses between endpoints

↥

Plot

before Chronic lower respiratory diseases
after Chronic lower respiratory diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Chronic lower respiratory diseases

↥

Endpoint not on priority list, no data to show.