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Sleep apnoea

DOID EFO MESH SNOMED Endpoint Browser PheWeb

G6_SLEEPAPNO

sleep apnea: A disorder characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G47.3
Hospital discharge: ICD-9 3472
Cause of death: ICD-10 G47.3
Cause of death: ICD-9 3472

2 out of 7 registries used, show all original rules.

45212

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Check minimum number of events None

45212

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Include endpoints None

45212

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Remove individuals based on genotype QC

43899

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G6_SLEEPAPNO

Control definitions

Control exclude G6_NARCOCATA, G6_SLEEPDISOTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G47
Name in latin Apnoea intrasomnalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 43899 17701 26198
Unadjusted prevalence (%) 10.66 7.69 14.41
Mean age at first event (years) 56.02 56.31 55.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.65 [1.38, 1.97] 2.7e-8 2743
15 years 0.01 1.20 [1.04, 1.37] 1.2e-2 1175
5 years 0.00 2.47 [2.18, 2.80] 2.3e-45 735
1 year 0.00 4.34 [3.68, 5.13] 9.4e-67 248

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_SLEEPAPNO – Sleep apnoea
GWS hits: 28

Survival analyses between endpoints

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Plot

before Sleep apnoea
after Sleep apnoea

loading spinner Loading survival analyses plot