Vascular dementia (subcortical)

VD_SC

vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F01.2
Cause of death: ICD-10 F01.2

2 out of 7 registries used, show all original rules.

756

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Check minimum number of events None

756

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Include endpoints None

756

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Remove individuals based on genotype QC

735

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VD_SC

Control definitions

Control exclude F5_DEMENTIA, G6_ALZHEIMER, G6_AD_WIDE

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 F01
Name in latin Dementia vascularis subcorticalis

Summary Statistics

Key figures

All Female Male
Number of individuals 735 274 461
Unadjusted prevalence (%) 0.18 0.12 0.25
Mean age at first event (years) 79.30 80.94 78.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: VD_SC – Vascular dementia (subcortical)
GWS hits: 2

Survival analyses between endpoints

Plot

before Vascular dementia (subcortical)
after Vascular dementia (subcortical)

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Drugs most likely to be purchased after Vascular dementia (subcortical)

Endpoint not on priority list, no data to show.